Velasof Tablet (Sofosbuvir (400mg) + Velpatasvir (100mg)
COUNTRY OF ORIGIN | India |
---|---|
DOSAGE FORM | Tablets |
GENERIC NAME | Sofosbuvir/Velpatasvir |
INDICATION | Treatment of Chronic hepatitis C virus (HCV) infection |
PACKAGING | 28 tablets in 1 strip |
MANUFACTURER | Hetero Drugs Ltd |
COMPOSITION | Sofosbuvir (400mg) + Velpatasvir (100mg) |
VELASOF TABLET is a combination of Sofosbuvir and Velpatasvir which belongs to the group of medicines called Antiviral agents. It is used to treat chronic (long-term) Hepatitis C infection.
Hepatitis C infection is a viral infection caused due to hepatitis C virus. It predominantly affects the liver and causes severe liver damage. It spreads mostly through contact with blood from an i

nfected person (such as through sharing needles).
It is suitable for use both in adults and in children (aged 3 years or above). Before taking VELASOF-TABLET inform your doctor if you have diabetes, kidney problems or any other liver problems apart from hepatitis C infection (such as liver transplant or hepatitis B infection). Do not take it without consulting your doctor if you are pregnant or breastfeeding.
During treatment, your doctor will regularly monitor your blood sugar levels and blood count to access improvement in your health condition and to avoid the risk of unwanted side effects.
The most common side effects are headache, tiredness and skin rashes. Consult your doctor if they trouble you.
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USES
- Treats chronic Hepatitis C infection
HOW IT WORKS
It is an antiviral agent. It acts by blocking the actions of certain viral enzymes (HIV-reverse transcriptase) that is required for the viral cell to grow and multiply. As a result, it controls the multiplication of harmful viral cells within the body which reduces the severity of the infection.
DIRECTIONS FOR USE
Take VELASOF-TABLET as directed by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. It can be taken with or without meals.
Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and severity of the infection. Do not stop taking it without consulting your doctor as it may reduce its effectiveness.
SIDE EFFECTS
COMMON
- Headache
- Tiredness
- Skin rash
RARE
Stop taking it and contact your doctor immediately if you experience any of the following side effects:
- Signs of allergic reactions (such as skin rash, itching, swelling of the face, lips, nose, throat which causes difficulty in breathing or swallowing)
- Severe skin reactions causing widespread skin rashes with severe itching, blistering and peeling of skin, accompanied with fever, flu-like symptoms and ulcers in the mouth, eyes and/or genitals)
HOW TO MANAGE SIDE EFFECTS
Headache:
Rest and relax. Keep yourself hydrated by drinking plenty of fluids such as water or electrolytes. Applying a pain-relieving balm on your forehead can be beneficial. Do not consume excessive alcohol, as it could aggravate your headache. Consult your doctor if your headache worsens.
WARNING & PRECAUTIONS
PREGNANCY
There is no proper information regrading the use during pregnancy. Therefore, if you are pregnant or think you may be pregnant, consult your doctor before taking this medicine. Pregnancy should be avoided if this medicine is combined with another antiviral agent known as ribavirin.
BREASTFEEDING
It may pass through the breast milk. Therefore, it is not recommended for use in breastfeeding women. Consult your doctor for advice before taking it.
DRIVING AND USING MACHINES
Do not drive or handle any machines if your ability is affected.
KIDNEY
It should be used with caution in patients with kidney problems (such as dialysis). Therefore, consult your doctor before taking it.
LIVER
It should be used with caution in patients with other liver problems apart from hepatitis C infection such as awaiting a liver transplant or hepatitis B infection. Therefore, consult your doctor before taking it.
ALLERGY
Do not take it if you are allergic to Velpatasvi-r or Sofosbuvir.
HEART DISEASE
It should be used with caution if you have heart problems. Consult your doctor for advice.
OTHERS
Before taking, inform your doctor if you:
- Are taking medicines for any on-going viral infections
- Have diabetes
Use in Paediatrics:
It is not recommended for use in children aged below 3 years. Therefore, consult your doctor before taking it.
Use in Geriatrics:
It should be used with caution in elderly people. Therefore, consult your doctor before taking it.
INTERACTIONS
A. Drug – Drug interactions:
Before taking it inform your doctor if you are taking any of the following medicines such as:
- Rifampicin, rifabutin, rifapentine (used to treat tuberculosis)
- St. John’s wort (a medicine used to treat depression)
- Medicines used to treat epilepsy (such as carbamazepine, phenobarbital, phenytoin, oxcarbazepine)
- Rosuvastatin (a medicine used to treat high blood cholesterol levels)
- Amiodarone, digoxin (used to treat irregular heart rate)
- Warfarin, dabigatran, vitamin k antagonists (used for blood thinning)
- Medicines used to suppress your immune system (such as tacrolimus, cyclosporine)
- Tenofovir disoproxil fumarate, tipranavir (used to treat HIV infection)
- Medicines used to treat stomach ulcers or heartburn (such as aluminium hydroxide, omeprazole, lansoprazole, rabeprazole, pantoprazole, esomeprazole, famotidine, cimetidine, nizatidine or ranitidine)
Overdosage:
If you or anyone else accidentally took more, consult your doctor immediately.
Angela (verified owner) –
“I’m on the path to recovery with this effective chronic HCV treatment. Life-changing results and improved well-being.”
Octavia (verified owner) –
“Living with chronic HCV is tough, but this medication is making a significant difference. Grateful for the progress.”