Bortenat Injection
COUNTRY OF ORIGIN | India |
---|---|
DOSAGE FORM | Injection |
GENERIC NAME | Bortezomib |
INDICATION | Â Non-Hodgkin’s Lymphoma (NHL) |
MANUFACTURER | Natco Pharma Ltd |
PACKAGING | 1 injection in 1 vial |
COMPOSITION | Bortezomib (2mg)
Bortezomib (3.5mg) |
PACK SIZE | 1 Injection/s, 3 Injection/s, 6 Injection/s, 9 Injection/s |
PRODUCT INTRODUCTION
Bortenat Injection is used in the treatment of multiple myeloma and mantle-cell lymphoma. It shows its working by stopping or slowing down the growth of cancer cells.
It is given as an injection by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
Fatigue, nausea, vomiting, and loss of appetite are some common side effects of this medicine. You may be advised to drink plenty of fluids every day during the treatment. You should not drive or operate machinery as medicine may cause tiredness and dizziness. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels.
Before taking Bortenat-Injection, consult with your doctor if you have any liver, kidney, heart disease or bleeding problem. It is important to consult a doctor if you develop symptoms like memory loss or trouble in thinking. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
USES OF BORTENAT INJECTION
- Multiple myeloma
- Mantle-cell lymphoma
BENEFITS OF BORTENAT INJECTION
Understanding Myeloma Cancer: Causes, Symptoms, and Risk Factors
Myeloma cancer, also known as multiple myeloma, is a malignancy that affects plasma cells in the bone marrow. It arises when these plasma cells become cancerous, multiplying uncontrollably and displacing healthy blood cells. To comprehend this disease, it’s essential to explore its origins, recognize its common symptoms, and understand the risk factors associated with its development. While the exact cause of myeloma cancer is not fully understood, certain risk factors such as age, family history, and exposure to radiation or specific chemicals can increase one’s susceptibility. Recognizing the causes, symptoms, and risk factors is crucial for early detection and effective management.
Symptoms and Diagnosis of Myeloma:
Myeloma often presents with non-specific symptoms that can initially be subtle, making diagnosis challenging. Common signs may include bone pain, fatigue, anemia, recurring infections, and kidney issues. To establish a diagnosis, healthcare professionals employ a combination of blood tests, bone marrow biopsies, imaging studies, and other diagnostic techniques. Timely and precise diagnosis is crucial for determining the disease’s stage and developing a personalized treatment plan.
Understanding Multiple Myeloma Prognosis:
Multiple Myeloma prognosis refers to the medical assessment and prediction of the likely course and outcome of this complex blood cancer. It involves evaluating factors such as the stage and extent of the disease, the patient’s overall health, and the response to treatment. Prognosis is an essential aspect of managing Multiple Myeloma, as it helps both patients and healthcare providers make informed decisions regarding treatment and care plans. It’s important to understand that the prognosis for Multiple Myloma can vary widely from one individual to another.
Symptoms and Diagnosis of Mantle Cell Lymphoma:
Mantle Cell Lymphoma often presents with symptoms such as painless swelling of lymph nodes, fatigue, night sweats, and unexplained weight loss. Diagnosis involves a combination of physical examination, imaging tests, blood work, and a lymph node biopsy. Flow cytometry and genetic testing are used to confirm the presence of MCL and its specific subtype. The disease is then staged to determine its extent and spread, which guides the treatment plan.
SIDE EFFECTS
Common side effects of Bortenat
- Low blood platelets
- Fatigue
- Peripheral neuropathy (tingling and numbness of feet and hand)
- Psychiatric disturbances
- Nausea
- Vomiting
- Loss of appetite
- Fever
- Anemia (low number of red blood cells)
- Diarrhea
- Decreased appetite
- Decreased white blood cell count (neutrophils)
- Constipation
Side Effects and Precautions Associated with Bortezomib Treatment
While Bortezomib has proven to be a valuable tool in cancer therapy, it does come with a range of potential side effects and precautions. Common side effects include nausea, diarrhea, peripheral neuropathy (nerve damage), and low blood cell counts. Patients may also experience more severe side effects, such as blood clotting disorders and heart problems, though these are less common. Due to its potential for toxicity, patients receiving require close monitoring by healthcare professionals. Precautions often involve adjusting treatment dosages, managing side effects, and addressing underlying medical conditions. Understanding and managing these potential complications is essential for safe and effective treatment.
Bortezomib Drug Interactions and Side Effects: Safety Considerations
Like many medications, bortezomib can interact with other drugs and cause side effects. Common side effects include gastrointestinal symptoms like nausea and diarrhea, peripheral neuropathy (nerve damage), and myelosuppression, leading to low blood cell counts. More severe side effects, although less common, can include heart problems and blood clotting disorders. Due to its potential for toxicity, careful monitoring of patients receiving bortezomib is necessary. Healthcare providers need to consider drug interactions and manage side effects to ensure patient safety during treatment.
HOW TO USE BORTENAT INJECTION
HOW BORTENAT INJECTION WORKS
SAFETY ADVICE

Alcohol


Pregnancy

Breast feeding

Driving
It might cause tiredness, dizziness, fainting, or blurred vision which may affect your ability to drive.

Kidney
Limited information is available on the use of Bortenat-Injection in these patients.

Liver
Legacy (verified owner) –
“No more dragging through illness. This antiviral medicine is my energy booster.”