Ondem Injection 4ml (Ondansetron 4mg)
| COUNTRY OF ORIGIN | India |
|---|---|
| DOSAGE FORM | Injection |
| GENERIC NAME | Ondansetron |
| INDICATION | Nausea |
| PACKAGING | 4 ml Injection in 1 vial |
| MANUFACTURER | Alkem Laboratories Ltd |
| COMPOSITION | Ondansetron (2mg/ml) |
INTRODUCTION
Ondem Injection 4ml (Ondansetron 4mg) contains Ondansetron which belongs to a group of medicines called anti-emetics, which help to stop feeling or being sick. It is indicated to prevent and treat nausea and vomiting induced by cytotoxic therapy and radiotherapy and post-operative nausea and vomiting. This medicine works by blocking the action of serotonin levels in the brain which causes nausea and vomiting during chemotherapy or any other surgery.
Cytotoxic chemotherapy triggers the release of serotonin from the enterochromaffin cells of the small intestine. The released serotonins stimulate the vagal afferents through the 5-HT3 receptors and initiate the vomiting reflex. Ondansetron is a selective 5-HT3 receptor antagonist which blocks serotonin, both peripherally on vagal nerve terminals and centrally in the chemoreceptor trigger zone. It works by blocking serotonin in the brain which causes nausea and vomiting during anti-cancer treatment (chemotherapy) or after surgery.
Before receiving ONDEM, tell your doctor if you have liver, kidney or heart problems, pregnant women and breastfeeding mothers. Your doctor will administer the right dose depends on your child’s age and body weight. The common side effects are headache, constipation and dizziness.
USES OF ONDEM
- Cancer chemotherapy-induced nausea and vomiting
- Postoperative nausea and/or vomiting
HOW ONDEM WORKS
ONDEM is a selective 5-HT3-receptor antagonist which blocks serotonin, both peripherally on vagal nerve terminals and centrally in the chemoreceptor trigger zone. It works by blocking serotonin in the brain which causes nausea and vomiting during anti-cancer treatment (chemotherapy) or after surgery.
DIRECTIONS FOR USE
ONDEM should be only given by a doctor or nurse. Your healthcare provider will administer as intravenous injection (into a vein) or, after dilution, as intravenous infusion.
SIDE EFFECTS OF ONDEM
COMMON
- Headache
- Sensation of flushing and warmth
- Constipation
- Pain, redness, burning at injection site
RARE
- Dizziness during rapid intravenous administration
- Skin rash
- Transient visual disturbances (blurred vision)
- Chest pain
- Temporary loss of vision
HOW TO MANAGE SIDE EFFECTS
Headache:
Rest and drink plenty of fluids.
Constipation:
Add fruits, vegetables whole grains and other high-fiber foods to your normal diet.
Dizziness:
Get up and move around to feel awake, take small naps to edge off the sleepiness. Give your eyes a break to avoid fatigue and eat a healthy food to boost energy.
WARNING & PRECAUTIONS
PREGNANCY
ONDEM is not recommended in the first trimester of pregnancy unless necessary. Consult your doctor for advice.
BREASTFEEDING
ONDEM is not recommended for use in breastfeeding women unless necessary. Discuss the risks and benefits with your doctor.
DRIVING AND USING MACHINES
This medicine has no or negligible effect on the ability to drive or use machines.
LIVER
ONDEM should be used with caution in patients suffering from liver function impairment or active liver diseases. Consult your doctor for advice.
ALLERGY
Tell if you are allergic (hypersensitive) to Ondansetron.
HEART DISEASE
ONDEM should be used with caution in patients suffering from uneven heartbeat or any other active heart diseases. Consult your doctor for advice.
Elliana (verified owner) –
“Jet lag warrior. After long flights, I turn to this nausea medicine to combat the dizziness and discomfort. Works like a charm.”
Catalina (verified owner) –
“Effective for hangovers. A heavy night out calls for this nausea medicine. It’s my secret weapon for recovering from a wild evening.”
Isabel (verified owner) –
“Emergency kit essential. I keep a bottle of this nausea medicine in my car for unexpected bouts of sickness. Always comes in handy.”