COUNTRY OF ORIGIN | India |
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DOSAGE FORM | Injection |
GENERIC NAME | Recombinant Human Erythropoietin Alfa |
INDICATION | Treatment of Anemia due to chronic kidney disease |
PACKAGING | 1 ml in 1 vial |
MANUFACTURER | Intas Pharmaceuticals Ltd |
COMPOSITION | Recombinant Human Erythropoietin Alfa (2000IU, 3000IU) |
PRODUCT INTRODUCTION
Epofit Injections is a medicine that helps your bone marrow to produce more red blood cells. It is used to treat a type of anemia caused by kidney disease. It is also used to treat anemia caused by cancer chemotherapy and by taking medicines to treat HIV.
Epofit Injection is given by injection either under the skin or into a vein which will be decided by your doctor. Usually, the injections are given by a nurse or doctor. The dose depends on your body weight and the cause of your anemia. Iron supplements both before and during treatment may make this treatment more effective. Epofit Inj needs to be stored in a fridge but used at room temperature.
The most common side effects of taking this medicine include nausea, vomiting, fever, and increased blood pressure. It may also cause flu-like symptoms such as headache, tiredness, dizziness and aches and pains. These side effects are most common at the start of treatment but if they persist your doctor may be able to suggest ways of preventing or reducing them. Tell your doctor straight away if you get any serious side effects, including seizures (fits). Sometimes this medicine can cause serious blood clots that need urgent medical attention.
Before using Epofit Inj you should tell your doctor if you have uncontrolled high blood pressure, heart disease, or gout (disease of joint pain). You should also tell him/her what other medicines you are taking in case they affect this treatment. Your blood pressure should be checked often during this treatment by you or your doctor. You may also need other regular medical tests to be sure this medicine is not causing harmful effects. It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding.
USES OF EPOFIT INJ
- Treatment of Anemia due to chronic kidney disease
- Treatment of Anemia due to cancer chemotherapy
BENEFITS
In Treatment of Anemia due to chronic kidney disease
In Treatment of Anemia due to cancer chemotherapy
Epoetin Beta: A Key Player in Red Blood Cell Production
Epoetin beta is another important variant of synthetic erythropoietin. It is used to treat anemia, particularly in chronic kidney disease patients, and can help raise haemoglobin levels and improve overall well-being by stimulating the formation of red blood cells.
Epoetin Alfa Injection: A Common Treatment for Anemia
Epoetin alfa is one of the most frequently used forms of epoetin in medical practice. It is employed to treat anemia, particularly in patients with chronic kidney disease or those undergoing chemotherapy. Epoetin alfa helps increase hemoglobin levels, alleviating anemia-related symptoms and improving patients’ quality of life.
Erythropoietin: Structure and Function
Erythropoietin is a glycoprotein hormone with a specific structure that enables it to bind to receptors on the surface of hematopoietic cells, initiating a cascade of events that promote red blood cell production. Understanding its structure and function is fundamental to developing therapies for conditions related to erythropoietin.
Erythropoietin Injection Types: Epoetin Alfa and Beyond
Erythropoietin injections come in various types, with epoetin alfa being one of the most common. There are also other synthetic erythropoietin formulations, each designed for specific medical applications. These variations offer flexibility in addressing different patient needs.
Hormone Erythropoietin EPO Receptors and Their Role in Erythropoiesis
EPO receptors are proteins found on the surface of erythroid progenitor cells in the bone marrow. These receptors are essential for EPO’s function. When EPO binds to its receptors, it initiates a signaling cascade that leads to the proliferation and differentiation of these cells into mature red blood cells.
SIDE EFFECTS OF EPOFIT INJ
Common side effects of Epofit
- High blood pressure
- Nausea
- Vomiting
- Fever
- Rash
- Joint pain
- Headache
- Insomnia (difficulty in sleeping)
- Chills
- Cough
- Bone pain
- Muscle spasm
- Dizziness
- Vascular occlusion
- Injection site irritation
- Stomatitis (Inflammation of the mouth)
- Weight loss
- Decreased white blood cell count (lymphocytes)
- Increased glucose level in blood
- Blood clot in the blood vessels
HOW TO USE EPOFIT INJ
HOW EPOFIT INJ WORKS
SAFETY ADVICE
Alcohol
Pregnancy
Breast feeding
Driving
Kidney
Regular monitoring of kidney function tests is advised while the patient is taking this medicine.
Liver
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